The advent of direct-to-consumer DNA testing means that anyone with cash and curiosity can now glimpse their genetic makeup. Personal genomics will soon become common currency as we strive to understand our individual risk profiles for disease, our physical and biological characteristics, and our personal ancestries. What are the benefits, consequences, and societal implications of the “Personal Genomics Revolution?” There is no better authority to bring to The Richmond Forum than Dr. George Church, professor of genetics at Harvard Medical School and creator of the Personal Genome Project.